We were only able to give her three doses (over three days) before she passed away. Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types. The longest one started maybe a five weeks ago and others are just beginning. 43 months. Scientific reports. One sachet per day for 3 days then 4 off. 728 posts. Please consider the Vitamin E. Seems like that might be an essential part. I have had 3 treatments fail in under a year. This reddit is for the discussion of cancer, cancer related news, stories of survival, stories of loss and everything else associated with the disease. Searching the literature, they found reports that fenbendazole had been shown to inhibit cancer growth. The paper on KRAS mutated lung cancer (screeining in cell lines) I figure anything that can't hurt and has the potential to help is worth a shot! Press J to jump to the feed. Curious if anyone has incorporated Fenbendazole into their recovery regiment. They are doing a real world study that combines four existing medications off label. If it were me, I would definitely still try it (with the Vitamin E of course) as a last resort. This drug is a dog dewormer that is safe for human use. Refrain from fighting, begging, and advertising. Standard of care currently consists of radiotherapy combined with chemotherapy of DNA-alkylating/methylating temozolomide (TMZ), which has increased the mean duration of patient survival to 15 months.1 Currently, only 10% of patients with GBM, including all post-treatment living con… Specially Niclosamide is known for its anti-cancer power independent of TP53 and can kill cancer cells when P53 is mutated and makes trouble …. The last thing the cancer industry needs is a cure. Here is an article about a man who took medication for dog parasites/dewormer and he believes it helped to cure his stage iv cancer. I just wanted to see if you had any updates on this. If you have animals, then you’ve definitely heard of Fenbendazole. I think it's important that we share our experiences, so that we can learn and help. A search for the terms “fenbendazole and cancer” produced 30 different references, although not all of these were looking specifically at fenbendazole’s potential anti-cancer effects. Hi, I hope you’re feeling better. Glioblastoma multiforme (GBM), which has been classified as a grade IV astrocytoma, is a highly aggressive tumor that invades early into surrounding brain tissues, making cure via surgical resection almost impossible. It also interferes with cancer cells abilities to use glucose. I'm not doing his whole protocol, just the 3 on/4 off with fenben. Have you looked at Care Oncology Clinic? That filler is a combination of milk sugar, cornstarch and calcium. I have no control over the content on any of the linked sites. Just curious, why does this get downvoted? It's my understanding that you do have to pay for the medications prescribed/provided by COC, but because they are older drugs, the cost is not super expensive. The only real side effects that I have had was some nausea, which may of may not have come from the Fenbendazole. An in-vitro test applying vitamin E succinate and/or fenbendazole against prostate cancer cells found that fenbendazole inhibited proliferation but did so even better when combined with vitamin E succinate. The first issue is the bulk. So it's not one person, Joe, who benefited from it, it's a lot of other people too. So, researchers tested the effect of fenbendazole on glucose uptake in human cancer cells. Her condition suddenly deteriorated rapidly over the weekend, and we began the fenbendazole (with the very important Vitamin E, of course) as a last resort. My mum is in a similar situation.. Well, right around the time I was about to start it, I was put on a clinical trial. I feel like I'm running out of options and am getting desperate. Clinical trials look at new ways to prevent, detect, or treat disease. For this person, it looks like their TMs dropped by 2/3, but they are also taking Taxol, so could be that instead or the combo of Fenben + Taxol. This study focused on tumor growth and how the drug affects it. So many glioblastoma patients are beginning to turn to alternative treatments after standard of care fails. I personally do not care for the forum format. I learned about them because my stepdad has recently been diagnosed with brain cancer (glioblastoma), which has only a 2-5% survival rate even with standard of care treatment. Scot is willing to do anything to live. I have Brain Cancer (Grade 2 Glioma). Objective: To evaluate the safety of fenbendazole in domestic cats. Fenbendazole - Cancer Support Group has 5,387 members. https://community.breastcancer.org/forum/8/topics/871246?page=7. Regardless, it was manageable with Zofran or Compazine. What dosage of fenben? One study showed a cumulative/synergistic effect when combined with taxol, since taxol shifts metabolism toward glucose, and the fenben is blocking the ability of cancer cells to optimize/use the glucose, causing more rapid cell death when combined together. However, I am just wondering if alternatives will be helpful as well. Animals: 28 six- to seven-month old domestic short-hair cats. I figure it's like being on a trial drug. Desperate times call for drastic measures. There are much more promising clinical trials than this.

Dosage: Each box includes treatment for 1 Dog. This reddit is for the discussion of cancer, cancer related news, stories of survival, stories of loss and everything else associated with the … You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. It's from the clinical data. Up to 5 % of people can experience stomach discomfort or diarrhea when taking large quantities of fenbendazole with no breaks. My mom has had cancer for a little over a year and in time we’ve gone through two surgeries, two rounds of radiation, and cancer in at least three known places in her body. Press J to jump to the feed. 2018 Aug 9;8(1):11926. doi: 10.1038/s41598-018-30158-6. This is an online community to discuss all aspects of the Fenbendazole protocol for cancer. https://www.nature.com/articles/s41598-018-30158-6?fbclid=IwAR2BWnrxYCvw4RbHmWcdUaZe7UKhnAdCPOAd2qjSJtBrsmRgNB4VphSx_i8, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/?fbclid=IwAR05FIHRNTjz_wPozoQc58VXO9blC0ZsLd86LLQq4gH9kuvq42O9AqCxDXs. I have stage iv metastatic breast cancer. Fenbendazole, is a drug used typically not for humans like Mebendazole, but for … Microtubule effects are only one of three ways it helps kill cancer cells. Seems like the Vitamin E is likely an essential piece. Background/aims: To evaluate the anticancer activity of fenbendazole, a widely used antihelminth with mechanisms of action that overlap with those of the hypoxia-selective nitroheterocyclic cytotoxins/radiosensitizers and the taxanes. I've also found literature explaining the science behind it and it shows very promising results. The truth of the matter is cancer is scary. Stephan Stahl. Fenbendazole’s ability to preferentially kill of malignant cells without harming healthy cells is another of its proposed properties. I'll keep you posted on how it goes. This group explores and celebrates the successes of the repurposed drug Panacur (fenbendazole) to cure cancer. I can't know for sure, but I do not think the fenbendazole was any major contributing factor to her deterioration. The data are summarised and discussed in relation to suggested mechanisms of action. Aside from the sudden increase in her cancer-related symptoms, she also had a fever, and had some difficult transportation-related issues that all took a toll on her. Also, note that the research seems to suggest that fenbendazole would need to be used in conjunction with certain vitamin supplements. It is a common drug for veterinary use.… 2 Comments. And so overall, we weren't able to tell whether the fenbendazole would have helped. One packet of Panacur C is 222 mg of Fenbendazole and 778 mg filler. This becomes a … More Information. Diet containing the anthelminthic fenbendazole is used often to treat rodent pinworm infections because it is easy to use and has few reported adverse effects on research. If this is your first visit, be sure to check out the FAQ by clicking the link above. " Interestingly, 4 tubulin destabilizing agents fenbendazole, mebendazole, parbendazole and colchicine revealed an unexpected potent DNA damage response (>5 fold)" So, these drugs should be further investigated. The original group is being turned off and moved to a forum. What is there to lose? Procedure: Cats were randomly assigned to 1 of 3 treatment groups or a control group (n = 7/group). The last thing the cancer industry needs is a cure. Hoping for good results! Then, by trial and error, they determined that the related drug mebendazole—which has been used for the last 60 years to treat parasites in the human gastrointestinal tract—might also hold potential for stalling glioblastoma. Definitely make sure you get the Vitamin E. I'm guessing that's in your multivitamin, though. In the same group of drugs as Mebendazole, a group called benzimidazoles, there is another anti-worm drug called Fenbendazole. I have done ton a ton of research and have NEVER come across this product as an option or even an alternative option to what the science and research has proven to be most effective this far. ... help Reddit App Reddit coins Reddit premium Reddit gifts. I'm trying it, have done one round so far. She did lose her voice shortly after taking her first dose of fenbendazole, but honestly that could have just been the fever. Original Poster. Based on the evidence presented, it is proposed that … I hope you’re okay. My father has SCLC and is receiving chemotherapy. Reddit is a network of communities based on people's interests. There … "AACR: Merck's Keytruda, up for new FDA nod, spurs lengthy responses in small cell lung cancer". All are welcome. Keep us posted. Update. Press question mark to learn the rest of the keyboard shortcuts. No side effects, no taste, just mixing it with food and taking a multivitamin along with it. There is some promising evidence in studies with mice and rats re: enhancing the effectiveness of chemo in treating breast cancer. Fenbendazole for cancer treatment . Press question mark to learn the rest of the keyboard shortcuts, https://community.breastcancer.org/forum/8/topics/871246?page=7. Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. Citation Dogra, K et al. He also takes Vit E as the research shows that Vit E and Fenbendazole worked better on prostate cancer. Tuesday 18th June 2019. Very curious. Hi everyone! Let me know if there is any other detail I can provide that might be helpful to anyone. Hi, just wanted to see if you had any updates on this. However, during fenbendazole treatment at our institution, an established human lymphoma xenograft model in C.B-17/Icr-prkdcscid … Fenbendazole did this by inhibition of an enzyme called hexokinase. Possibly a decrease in kidney function as well at the time. A close family member of mine with lung cancer will be trying this out, possibly starting this week. Two different type of cancer cells, H460 and A549 cells, were treated with fenbendazole. But I am not a doctor, so take my .02 with a grain of salt. You can see how close they are. Written by dtcdirector May 14, 2020. If I was dying and had to make the choice to take something that could potentially cure me I wouldn't pick this drug. I'm not responding to chemo and they say it is terminal so I'm trying this. Significantly, there are also two case reports of anti-cancer activity in humans. I started the protocol using Panacur C. That was fine to start out with, but there were some issues with it. Clinical trials are research studies that involve people. "Fenben acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways.". ... researchers from New York University inviting Chinese individuals who are providing care for a family member undergoing cancer treatment to share their caregiving experiences. Fenbendazole is a drug used for parasite and anti-worm treatments in animals. Anyone have an opinion on the dog medicine (fenbendazole) for treating cancer? Only one person (see page 16 - snooky1954) so far has had any results to report, and this is only for blood tumor markers, so not much in the way of robust supportive evidence. Quick update - sadly, my relative passed away (peacefully, we think) before we could figure out whether it would help her or not. bongtom. Doses should be divided accordingly in this situation. The anti-worm drug Fenbendazole has anti-cancer potential. They have found that a group of medications used to treat parasitic diseases or helminthic manifestations can, in fact, help cancer patients. People with severe liver or kidney failure have lower medication excretion rates, therefore, fenbendazole can accumulate and cause unexpected side-effects. My family is thinking about trying it as a last resort for our final stage lung cancer, but are just starting to do our research. Some others are up for results reporting soon. The clinical trials on this list are studying Mebendazole. Have any of you tried it? Pregnant Dogs: A slightly altered dosage of 25 mg/kg fenbendazole may be used when treating pregnant dogs. New comments cannot be posted and votes cannot be cast. All trials on the list are supported by NCI.. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. HIs energy has increased and he feels much better. And how often are you taking it? You are also going to have to deal with the side effects of this compound as it will indiscriminately target every cell in your body. Thank you for visiting FenBenForum.com. Also using frankincense topically as well as diffusing it. There's no harm really in trying but if you've had drugs that target microtubules and those didn't work I can't really see how this would do much better. Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. What Is Fenbendazole and How Can It Affect Cancer Treatment? Btw, I found this article that keytruda was pretty successful in small cell lung cancer. I wanted to find out if this protocol helped you? The vitamin concoction used included B, D, K, E, and A. Good luck, I hope it works for you! At that point, I'm sure the fenbendazole didn't help either... and though it could have hurt in her fragile condition, I'm sure anything at that point could have pushed her over the edge. Hey poopies_monkey. Find communities you're interested in, and become part of an online community! Fenbendazole 3 days on, 4 days off.My name is Scot Pekarek. Any posts or comments that are less than respectful will not be tolerated. Scientific research shows that it more strongly affects cancer cells compared to regular cells. Reply Reply Author. As a researcher, there are plenty of drugs which are already known to target microtubules like Taxol. They seem to be having some success. Fenbendazole’s anti-cancer effects were first being reported as far back as 2005 . I'm a little nervous to do it with my current treatment. Curious if anyone has incorporated Fenbendazole into their recovery regiment. It appears a great community for sharing info, tips and outcomes. In fact, it can’t afford a cure. This community at this link is trying it together. Last week we had to admit her to the ER because as we now know, a series of small brain tumors are taking away her ability to walk right, tell time, sleep, think, see etc. Have you seen any results from taking this, positive or negative? Since he has been on the Fenbendazole, the swelling in his legs is gone and they are back to normal. Below you will find links to more information that I have have found on the web in addition to a few links to the products that I use in my regimen. Here are a couple links to info. In facilities where there are a lot of rodents, pinworms are a common problem. Cats in the treatment groups were given fenbendazole at a dosage of 50, 150, or 250 mg/kg, PO, every 24 hours for 9 days; control cats were given a placebo. For the last couple of days I have been glued to the internet researching drugs and current clinical trials. Fenbendazole is an antiparasitic drug commonly used to treat parasites (heart worm in dogs and other parasites in humans). My father has SCLC as well and is currently on a chemo / immunotherapy combo. https://www.odditycentral.com/news/man-claims-cheap-dog-deworming-medicine-cured-his-terminal-cancer.html. I will post more information next week when I have more evidence that Fenbendazole is working. In this study, Fenbendazole alone did not have an inhibitory effect. 2018. Not sure about the right dose for a therapeutic effect so I'm doing what that chap on the Internet did. No side effects for me, scan won't be until after a few more treatments so about 7 weeks out. Discussion. Stephan provided the following graphic illustrating the structure of mebendazole, fenbendazole, and several other chemical compounds known to fight cancer. Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways Sci Rep . What are your thoughts regarding Fenbendazole? Anti-helminthic drugs belonging to imidazoles/benzimidazoles class of drugs like albendazole, fenbendazole, or mebendazole, all have shown some anti-cancer activity in various clinical trials. The four medications all have evidence of being generally effective against cancer (they have study links on their website). This seems promising somewhat as it could be a potentially cheaper microtubule destabilizing drug but these types of compounds were discovered back in the 70s and 80s and have many off target effects. /r/lungcancer is a place for stories, advice, etc. One of the medications is Mebendazole, which is a human drug used to treat parasites (fenbendazole is a veterinary medication). December 19, 2019 Aug 9 ; 8 ( 1 ):11926. doi: 10.1038/s41598-018-30158-6 part of an online!. Animals, then you ’ ve definitely heard of fenbendazole, but honestly that could potentially cure me i definitely... Any of the linked sites cells is another of its proposed properties fenbendazole with no.! 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