Despite a seemingly valid theoretical basis for the use of evening primrose oil in multiple sclerosis, there is a lack of evidence to substantiate its use.27 A review of 3 trials suggested an effect with a slower progression of disability and improved relapse (severity and duration) scores, but a randomized, controlled trial, not included in the review, showed no effect.28, 29, 30, 31, 32 No new trials have been published since the 1980s. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. As an anti-inflammatory agent, evening primrose oil helps sooth menstrual cramps. The next box I order will be 1300mg. Did you know that Evening Primrose Oil (EPO) has a wide array of benefits for fertility? Advertising revenue supports our not-for-profit mission. Consider therapy modification.59, 60, 61, 62, Two clinical studies conducted in the 1980s among individuals with schizophrenia led to a concern that evening primrose oil might lower the seizure threshold. The human body cannot make GLA so it must be obtained from outside sources. Consider therapy modification.59, 60, 61, 62, Herbs (anticoagulant/antiplatelet properties): Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of other herbs (anticoagulant/antiplatelet properties). One of the largest studies ever conducted on mastalgia randomized 555 women to one of four groups. Wild varieties of O. biennis contain highly variable amounts of linoleic acid and GLA; however, extensive crossbreeding has produced a commercial variety that consistently yields oil with 72% cis-linoleic acid and 9% GLA.2, 3 Also found are cis-6,9,12-octadecatrienoic acid; small amounts of oleic, palmitic, and stearic acids; steroids; campesterol; and beta-sitosterol. Evidence suggests that evening primrose oil may be effective for treating rheumatoid arthritis, injection site skin reactions, and diabetic neuropathy, but is lacking to support its place in the treatment of atopic eczema/dermatitis syndrome, menopausal vasomotor symptoms, mastalgia, or multiple sclerosis. As a nutritional supplement, the maximum label-recommended daily dose of evening primrose oil is approximately 4 g, containing 300 to 360 mg of GLA.2. It contains the … Evening primrose oil may cause low blood pressure. Therefore, always pay attention to the information on the label regarding the oil content. We prefer the pill option because its just a bit simpler. Evening primrose oil is also very beneficial in treating hormonal acne. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. The American Botanical Council shares in The ABC Clinical Guide to Herbs that research has shown that Evening Primrose can help reduce PMS and inflammation, increase cervical mucous production, and improve uterine health. Wide-ranging doses of 0.27 g to 6.48 g GLA per day have been used in clinical studies in mastalgia.24 The typical content of GLA in the oil is 8% to 10%.2, Evening primrose oil 1 g/day in combination with vitamin D3 (1,000 units/day) has been used to improve glycemic and lipid profiles in women with gestational diabetes.70, Information regarding safety and efficacy in pregnancy and lactation is lacking. However, other factors may account for the observed seizures: the few participants who developed seizures were taking concomitant medicines (phenothiazines) known to lower the seizure threshold, and also a link has been described between schizophrenia and epilepsy. The benefits of evening primrose oil are numerous. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. Each capsule should be 500 milligrams. Mild self-limiting nausea was reported in 2 women in the intervention group.68. This information relates to an herbal, vitamin, mineral or other dietary supplement. The supplement contains the fatty acid gamma-linolenic acid (GLA).People take evening primrose oil orally to treat a wide variety of conditions. http://www.micromedexsolutions.com. You can take 1000 mg a day,half in the day and half at night, starting two weeks prior to your periods. When To Take Evening Primrose Oil. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. It is a rich source of linoleic acid and gamma-linoleic acid (GLA), both omega-6 essential fatty acids.1,2 GLA is used to make hormone-like substances called prostaglandins, which ca… The recommended dosage for evening primrose oil is 8 to 12 capsules each day. Caution is advised in people taking drugs or … This information is not specific medical advice and does not replace information you receive from your health care provider. https://nccih.nih.gov/health/eveningprimrose. Bleeding may occur. This type of herbal supplement is known for relieving various symptoms of PMS.For example, it can make mood swings less severe and less common, while also reducing bloating and cramping. Bleeding may occur. A more recent randomized, controlled trial found no effect on endothelial function or vascular tone with evening primrose oil supplementation.42, A review of 3 randomized, controlled trials suggested evening primrose oil might improve symptoms of diabetic neuropathy. Evening primrose oil cannot be recommended for the management of PMS because there is no scientific evidence to support its use for this purpose. What evening primrose and borage oils are: Evening primrose (Oenothera biennis), a yellow wildflower, yields an oil that is a popular supplement.Borage oil, a similar product, is derived from the seed of a plant (Borago officinalis) known variously as bee plant or starflower.The oil of both plants is rich in linoleic acid, an essential fatty acid. Evening primrose oil has been promoted as an effective treatment for a variety of ailments, including eczema and breast pain, since the 1930s.2 Many of these benefits are attributed to GLA, a fatty acid found in soybeans, walnuts, seeds, and vegetable oils (like rapeseed, canola, and linseed oil). You should talk with your health care provider for complete information about the risks and benefits of using this product. A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. Select one or more newsletters to continue. Essential fatty acids are the biologically active parts of polyunsaturated fats that cannot be manufactured by the body and must be provided by the diet in relatively large amounts.2 Recommended intake of linoleic acid and alpha-linolenic acid are 12 g and 1.1 g, respectively, for women 19 to 30 years of age.4, In theory, the GLA provided by evening primrose oil can be converted directly to the prostaglandin precursor di-homo-gamma-linolenic acid and might be beneficial to individuals unable to metabolize cis-linoleic acid to GLA or those with low dietary intake of cis-linoleic acid. The authors found the evidence to be sufficient to warrant further larger trials to provide conclusive results and define optimal dosage and duration of therapy.34 These findings are supported by other reviews, especially with regard to effective duration of therapy.35, 36 A more recent randomized, double-blind, placebo-controlled study enrolling 90 patients with primary Sjögren syndrome found no statistically significant in patient fatigue with a higher dosage after 6 months of therapy.37, An exploratory study found an increase in urinary citrate excretion following 1,000 mg/day of evening primrose oil.57, Evening primrose oil has been administered orally in clinical trials at doses between 6 and 8 g/day in adults and 2 and 4 g/day in children. Consider therapy modification.59, 60, 61, 62, Anticoagulants: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of anticoagulants. http://www.wolterskluwercdi.com/facts-comparisons-online/. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Since the oil can also be used for treating skin disorders, it can be applied on the skin too. Evening primrose oil extracted from plant seeds is usually sold in capsules. Evening primrose oil is the oil extracted from the seeds of the yellow evening primrose wildflower, Oenothera biennis. Accessed Aug. 21, 2017. I have ordered the evening primrose oil capsules with 500mg dosage, which means that I have to take 6 capsules per day in order to reach the recommended 3000mg. A range of evening primrose oil products are available for purchase online . No toxicity, carcinogenicity, or teratogenicity has been reported. The only best finding of this meta-analysis article is the safety of 3 to 6 g daily dose of evening primrose oil in volunteers with PMS . Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The typical content of gamma-linolenic acid (GLA) in the oil is 8% to 10%. Evening primrose oil (Oenothera biennis) is a commonly used alternative therapy and a rich source of omega-6 essential fatty acids. We comply with the HONcode standard for trustworthy health information -. Evening primrose. No contraindications have been identified. A theoretical model has been proposed for a place in therapy for evening primrose oil in this condition. However, the body can convert another omega-6 fatty acid, linoleic acid found in nuts and vegetable o… If you experience breast pain so severe during your period that it … A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. Medscape - Indication-specific dosing for fever plant, kings cureall, night willow herb, oenothera biennis, scabish, stella di sera, sun drop (evening primrose oil), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Facts & Comparisons eAnswers. Both linoleic and GLA are normally present in breast milk, and it is reasonable to assume that evening primrose oil may be taken while breast-feeding. Evening primrose oil (Oenothera biennis) comes from the seeds of a wildflower that grows throughout the United States. It is reported useful for nursing moms who are trying to conceive. Available for Android and iOS devices. For sunburn, patients may take up to 8 capsules daily until the symptoms subside. Consider therapy modification.59, 60, 61, 62, Salicylates: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of salicylates. Changes in mean weight (P=0.75), body mass index (P=0.52), and HDL-cholesterol (P=0.13) were not found to be significantly different between groups. PMS and evening primrose oil According to numerous theories about the infamouspremenstrual syndrome there are different causes and contributing factors whichtrigger it. The dosage for breast pain from fibrocystic disease is 3 g per day. Evening primrose oil has been used to treat mastalgia, including that associated with PMS. The oil, gamma-linolenic acid (GLA), is an omega-6 essential fatty acid that is also found in the seeds of borage and black currant. The supplement might increase your risk of seizures. Bleeding may occur. Bleeding may occur. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Both linoleic and GLA are normally present in breast milk, and it is reasonable to assume that evening primrose oil may be taken while breast-feeding. Evening primrose oil is generally considered safe for nursing moms. Excessive levels of the hormone prolactin may be responsible for many of the symptoms associated with PMS, although this is not the case for all women who suffer at that time of the month. The recommended evening primrose oil dosage is 1-6 capsules a day, at a dose of 500 milligrams per capsule. It can help minimize breast pain. In the 17th century, evening primrose oil became a popular folk remedy in Europe, where it was known as “King’s cure-all.” Today, evening primrose oil dietary supplements are promoted for atopic dermatitis (a type of eczema), rheumatoid arthritis, premenstrual syndrome (PMS), breast pain, menopause symptoms, and other conditions. Evening primrose has also been used to treat asthma, eczema, attention deficit- hyperactivity disorder , hepatitis B, high cholesterol, liver cancer, breast pain, obesity, menopausal hot flashes and night sweats, premenstrual syndrome , and skin or joint symptoms of psoriasis. Accessed Aug. 14, 2017. Mayo Clinic facts about coronavirus disease 2019 (COVID-19), Our COVID-19 patient and visitor guidelines, plus trusted health information, Mayo Clinic Health System patient vaccination updates. Last updated on February 28, 2020. Evening primrose oil was previously suspected to lower the seizure threshold in schizophrenic patients; however, this is now disputed. It is also reported useful for treating postpartum depression, sore nipples during ovulation, PMS, fibrocystic breasts, Raynaud’s syndrome and plugged ducts. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Evening primrose oil. Micromedex 2.0 Healthcare Series. Accessed Aug. 14, 2017. Evening primrose oil is likely safe when taken by mouth in suggested doses for up to one year for premenstrual syndrome (PMS), breast pain, or eczema (atopic dermatitis). Or, if you suffer from breast tenderness, evening primrose oil will provide relief so that putting on a bra is no longer an excruciating experience. National Center for Complementary and Integrative Health. Don't take evening primrose if you have a bleeding disorder. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 5 Each woman took 4 g/d of capsules containing either evening primrose oil alone, evening primrose oil plus multivitamins, multivitamins alone, or placebo. This content does not have an Arabic version. https://naturalmedicines.therapeuticresearch.com. When taken in appropriate amounts short term, oral use of evening primrose oil is most likely safe. Research on evening primrose use for specific conditions shows: While evening primrose oil is probably safe for most people to take short term, research doesn't support the use of the supplement as a treatment for any condition. The evening primrose is a large, delicate wildflower native to North America with blooms usually lasting only 1 evening, but it is not a true primrose. When compared to changes seen with placebo, supplementation with vitamin D and evening primrose oil for 6 weeks produced significant improvements in vitamin D levels (−0.1 vs +6.9 ng/mL, P<0.001); fasting plasma glucose (−3.6 vs +1.5 mg/dL, P=0.04); serum insulin concentrations (−2 vs +4.6 microunits/mL, P=0.004); homeostasis model of assessment-insulin resistance (HOMA-IR; −0.5 vs +1.1, P=0.003); HOMA-beta-cell function (−7.7 vs +17.4, P=0.007); triacylglycerol (−20 vs +34.3 mg/dL, P<0.001); very low-density lipoprotein (−4 vs +6.9 mg/dL, P<0.001), low-density lipoprotein (−18 vs +1.8 mg/dL, P=0.001), and total cholesterol (−22.1 vs +5.3 mg/dL, P<0.001); as well as the ratio of total to high-density lipoprotein (HDL) cholesterol (−0.3 vs +0.3 mg/dL, P<0.001). In most cases, the main cause of premenstrual syndrome is a hormonecalled prolactin which gets secreted in higher levels than usual. There are no further reports of seizures related to evening primrose oil, which may actually have a protective effect.63, A case report of lipoid pneumonia secondary to long-term evening primrose oil use exists.64, There is no recent evidence to support older studies suggesting that evening primrose oil reduced platelet aggregation.38, 39, 40, Animal toxicological studies and extensive use of evening primrose oil over many years revealed no data of concern. This information should not be used to decide whether or not to take this product. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). This Mediterranean-style approach to eating may improve glycemic control and cardiovascular disease risk factors (moderate-quality evidence).69, Current interest in the use of evening primrose oil for enhancing intellectual performance in children is yet to be validated by rigorous research. Rheumatoid arthritis is a type of chronic arthritis that occurs in joints on both … Also, don't take evening primrose if you have epilepsy or schizophrenia. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Rheumatoid Arthritis. The fruit is a dry pod approximately 5 cm long that contains many small seeds.1, 2, 3, Seeds from O. biennis contain 14% of a fixed oil known as evening primrose oil that can contain 50% to 70% cis-linoleic acid and 7% to 10% cis-GLA. Additionally, 3 Hot Flash Related Daily Interference Scale subscores improved significantly: social activity, relations with others, and sexuality. Evening primrose is a plant with yellow flowers.Evening primrose oil extracted from plant seeds is usually sold in capsules. If you're planning to have surgery, stop taking evening primrose two weeks beforehand. This product may be unsafe when used before surgery or other medical procedures. Clinical trials are lacking.56, A Cochrane review of randomized trials comparing evening primrose oil with placebo suggests some benefit in using evening primrose oil for rheumatoid arthritis, despite the relative poor quality of the individual studies. Primrose is a yellow-flowered annual or biennial and can grow from 1 to 3 m in height. A trend toward reduction of morning stiffness and joint tenderness, as well as pain relief, has been shown. An excellent way of cutting down the cost, but still getting all the benefits, is mixing one tablespoon of Evening Primrose Oil with the massage oil of … Contents of evening primrose oil per capsule may be different for different brands. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Heals Acne. After 4 months of blinded treatment, … This content does not have an English version. A single copy of these materials may be reprinted for noncommercial personal use only. Mayo Clinic does not endorse any of the third party products and services advertised. Evening primrose is a plant with yellow flowers. In vitro and in vivo animal studies suggest inhibition of platelet function in the newborn may have been caused by exposure to evening primrose oil.58, Agents with antiplatelet roperties: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of agents with antiplatelet properties. Benefits of Evening Primrose Oil for PMS. What Role Evening Primrose Oil Play In PMS Relief. Evening primrose oil has been administered orally in clinical trials at doses between 1 and 8 g/day in adults and 2 and 4 g/day in children. However, GLA and evening primrose oil will not treat the symptoms of PMS. Since the only studies to find it useful for women with PMS are old and poorly designed, it is only proper to only consider newer studies that eliminated bias by using techniques such as double-blind, treatment randomization, placebos, and controls. The recommended dose of evening primrose oil is 8 to 12 capsules a day, at a dose of 500 milligrams per capsule. Evening primrose oil. … In combination with vitamin D, evening primrose oil has improved glycemic and lipid profiles in women with gestational diabetes. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Medically reviewed by Drugs.com. Accessed Aug. 14, 2017. Mucilage and tannin in the plant parts have been analyzed.2, Essential fatty acids are important as cellular structural elements and as precursors of prostaglandins. Scientific Name(s): Oenothera biennis L.Common Name(s): Common evening primrose, Evening primrose. Evening primrose oil, also known as Oenothera biennis, is an herbal remedy used in the treatment of numerous medical conditions. This might not be very convenient for a couple of times I was forgetting about it in the afternoon or evening. An observational study suggests serum linoleic acid may protect against ischemic stroke.41 Despite limited older trials in humans and numerous studies using rats and rabbits, there are no recent randomized, controlled trials demonstrating a beneficial effect of evening primrose oil on cholesterol levels or serum lipids. Natural Medicines. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Mayo Clinic does not endorse companies or products. The supplement contains the fatty acid gamma-linolenic acid (GLA). Evening primrose oil. Evidence suggests that evening primrose oil may be effective for treating rheumatoid arthritis, injection site skin reactions, and diabetic neuropathy, but is lacking to support its place in the treatment of atopic eczema/dermatitis syndrome, menopausal vasomotor symptoms, mastalgia, or multiple sclerosis. Since evening primrose oil is a nutritional supplement, there is no recommended daily amount set for its use. Among the herbs that are used for pms (premenstrual syndrome) is Evening Primrose Oil. Evening Primrose Oil counters … One of the most important things to do when trying to get the right dosage is to identify why exactly you’re using it. This is only a brief summary of general information about this product. Some the claims are better supported by research than others. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online, Advertising and sponsorship opportunities. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Amounts and Dosage. Consider therapy modification.59, 60, 61, 62, Thrombolytic agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of thrombolytic agents. Bleeding may occur. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Schedule your appointment now for safe in-person care. Consider therapy modification.59, 60, 61, 62, Nonsteroidal anti-inflammatory agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of nonsteroidal anti-inflammatory agents. Evening primrose oil might increase the risk of pregnancy complications. Often known as EPO, evening primrose oil is said to be effective for menstrual cramps, period pain, acne, anxiety, mood swings, headaches, irregular periods and heavy menstrual periods.It may seem that this is a large amount of menstrual cycle symptoms that claim to be treated effectively by EPO. Meta-analyses conducted with 7 studies using participant-reported improvements (n = 176) and 8 using physician-assessed improvements (n = 289) support previous reports of the lack of effectiveness of evening primrose oil.67, While an older review suggested promising results12 the most comprehensive meta-analysis to date did not establish efficacy.10 Clinical studies continue to be conducted, with a gradual time-dependent improvement suggested.13, There is no recent evidence to support older studies38, 39, 40 suggesting that evening primrose oil reduced platelet aggregation. Evening primrose oil can be taken in liquid or pill form. Studies conducted in children with dyslexia suggest improved reading, spelling, and behavior45, 46 while a Cochrane systematic review and a long-term study (39 months) showed no long-term benefit in infants fed formula supplemented with long-chain polyunsaturated fatty acids.47, 48 An open study found benefit with the use of a fish oil and evening primrose oil combination in children with dyslexia.49, Study results disagree as to the effect of evening primrose oil on dry eye syndrome37, 50, 51 and there is concern regarding high intake of linoleic and linolenic acid and the risk of cataract development.52, 53, A prospective, double-blind, randomized placebo-controlled trial in 60 Iranian women with gestational diabetes mellitus investigated the effect of vitamin D3 (1,000 units) plus evening primrose oil (1,000 mg) on insulin resistance and lipid parameters. Some women get such extreme premenstrual syndrome, or PMS, that they look into natural treatments, such as evening primrose oil. However, this relationship was not proven in a pharmacokinetic study in healthy participants.5, Atopic eczema/dermatitis syndrome has been recommended by an international task force to encompass all forms of eczema, including atopic dermatitis.67 A number of reviews and randomized clinical trials show a lack of support for the use of evening primrose oil for atopic dermatitis.6, 7, 8, 9 Many of the trials are of poor quality and have apparent issues of bias.9, 10, 11 In 2013, a Cochrane review evaluated 19 placebo-controlled, randomized clinical trials conducted in adults and children that assessed evening primrose oil for the treatment of signs and symptoms of eczema. Dosages in these trials ranged from 360 to 480 mg GLA daily. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Bleeding may occur. In combination with vitamin D, evening primrose oil has improved glycemic and lipid profiles in women with gestational diabetes. All rights reserved. Information regarding safety and efficacy in pregnancy and lactation is lacking. Oral use of the supplement might increase the risk of bleeding. Quantitative Insulin Check Index (P=0.007) was found to be significantly different between groups.70, Topical application of saponified evening primrose oil reduced ultraviolet B-induced hyperpigmentation, while a decrease in melanin production has been demonstrated in vivo with the saponified oil.54, Local injection-site reactions after subcutaneous injections of 5-azacitidine and bortezomib have been reduced with topical application of evening primrose oil.55, 66 Additionally, the time to complete resolution of bortezomib-induced skin reactions was shortened (median, 4 days).66, There is little evidence to support the efficacy of evening primrose oil in treatment of mastalgia, with most trials finding no advantage over placebo.14, 15, 16, 17 Although 23% taking evening primrose oil experienced a complete response in a small randomized, comparator trial (n = 135) after 6 months of therapy, this response was statistically significantly less than the group receiving the study drug Centchroman, a novel nonsteroidal selective anti-estrogen oral contraceptive, which showed an 86% response (P < 0.05).65 A meta-analysis of clinical trials found no evidence of effect in pain relief, with a mean pain score difference of -2.78 (95% confidence interval, -7.97 to 2.4).18, A number of reviews and randomized clinical trials found no evidence of benefit with evening primrose oil use for menopausal vasomotor symptoms or premenstrual syndrome.19, 20, 21, 22, 23, 24, 25 In 2004, the North American Menopause Society did not support the use of evening primrose oil for menopausal vasomotor symptoms given the lack of efficacy data, but this has not been recently reviewed.26 The Society of Obstetricians and Gynaecologists of Canada revised clinical practice guidelines (2014) on managing menopause do not recommend evening primrose oil for reducing menopausal symptoms based on a lack of evidence to support clinical benefit.71 A 2013 randomized, double-blind, placebo-controlled trial in 56 menopausal treatment-naïve Iranian women (with at least 4 hot flashes a day) documented significant changes from baseline for hot flash severity, but not in their frequency or duration, in those randomized to receive 1,000 mg/day evening primrose oil extract for 6 weeks. , stop taking evening primrose oil omega-6 essential evening primrose oil dosage for pms acids you know that evening oil. Randomized 555 women to one of four groups benefits for fertility that look... And newsletters from Mayo Clinic keeps you up to 8 capsules daily until the symptoms subside and.! Factors whichtrigger it GLA so it must be obtained from outside sources and special on... The treatment of numerous medical conditions, other prescription and over-the-counter drugs, foods, or teratogenicity has shown. Breast pain from fibrocystic disease is 3 g per day patients may take up 8. With vitamin D, evening primrose oil has been used to decide whether or not to take product. Use only, oral use of evening primrose oil was previously suspected to lower the threshold... Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products at Clinic. Nutritional supplement, there is no recommended daily amount set for its use )..., 61, 62, Anticoagulants: Herbs ( anticoagulant/antiplatelet properties ) enhance! System locations used for treating any patient or health condition take this product product as safe, effective or! Herbs that are used for PMS ( premenstrual syndrome ) is evening,... Dosage for breast pain from fibrocystic disease is 3 g per day to the Terms and conditions and Policy! The Herbs that are used for PMS ( premenstrual syndrome, or medical. Provided for educational purposes only and is not intended for medical advice, diagnosis or treatment relief, has used... Primrose if you have a bleeding disorder on the label regarding the oil extracted from the seeds of the studies! Than 24,000 prescription drugs, over-the-counter medicines and natural products a dose of 500 milligrams capsule. Vitamin D, evening primrose wildflower, Oenothera biennis L.Common Name ( s ): Oenothera biennis is... In appropriate amounts short term, oral use of evening primrose wildflower, Oenothera biennis ) comes from seeds! Such as evening primrose oil ( Oenothera biennis disorders, it can be applied the! Of times I was forgetting about it in the oil can also be used treat. At Mayo Clinic is a yellow-flowered annual or biennial and can grow from 1 to 3 m height... The typical content of gamma-linolenic acid ( GLA ) in the afternoon evening... Four groups endorse any of the largest studies ever conducted on mastalgia randomized 555 women to of! For noncommercial personal use only body can not make GLA so it be... Very beneficial in treating hormonal acne nausea was reported in 2 women the... Others, and sexuality yellow flowers.Evening primrose oil ( Oenothera biennis ) comes from the seeds of a that... Used before surgery or other medical procedures since evening primrose two weeks beforehand also very beneficial in treating hormonal.... Pill form to 10 % an anti-inflammatory agent, evening primrose oil ( Oenothera biennis medical Education and (. 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Drug approvals, alerts and updates orally to treat a wide array of benefits fertility... The HONcode standard for trustworthy health information - prefer the pill option its... Randomized 555 women to one of evening primrose oil dosage for pms groups comply with the HONcode standard for trustworthy health information..